Exploiting the data mine

Exploiting the data mine
The inspiration for the first RSC ontology, the Reaction Ontology (RXNO), came from hearing about a gene ontology for biochemical processes being developed at the EBI. 'We realised that the chemical community had similar problems when discussing …
Read more on Royal Society of Chemistry

Systems biology surveillance decrypts pathological transcriptome remodeling
Focused examination of domain-specific gene ontology remodeling revealed a general enrichment of Cardiovascular Development in the truncation variants, with unique prioritization of “Cardiovascular Disease” exclusive to the cohort of down regulated …
Read more on BMC Blogs Network

Recursive splicing in long vertebrate genes
1b–d), and are enriched in Gene Ontology (GO) terms associated with the nervous system (Extended Data Fig. 1a). We therefore produced 1.5 billion paired-end total RNA sequencing (RNA-seq) reads from four post-mortem brains to search for new splicing …
Read more on Nature.com

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